Clean room design manual

A Guide to Cleanroom Design. What is a Cleanroom? A cleanroom is a room or space in which the level of particulate contamination is controlled within set levels. The construction, temperature, humidity, air flow patterns and pressure are controlled in such a way as to minimise the introduction, generation and retention of particles (such as. 2 Mechanical (HVAC) Engineering Design This HVAC design guideline written for healthcare facilities, is a consolidated document listing out the design requirements for all new construction and major renovation healthcare projects. Compliance to this document, which stipulates minimum performance design standards, ensures that facilities will. Clean Room Requirements:Airborne Particles1 1 WHO TRS , Annex 6, paragraph 8 Maximum permitted number of particle per m3greater than or equal to the tabulated size Atrest a In operation b Grade µm µm µm µm A 20

cleanroom space via shoes. Do not bypass these mats. • Cleanroom paper is the only paper allowed in this facility. Spiral and 3-ring notebooks of cleanroom paper are. available through various vendors, such as Fisher Scientific. • To maintain a cleanroom environment, while working in the facility no cosmetics or hair spray may be worn. Cleanroom structures may be built using conventional building techniques (bricks and motor) however the internal finish should be designed to suit the class of cleanroom. ISO class 8 and 9 cleanrooms may only require epoxy painted walls however this would be dependent on the levels of particles generated by people and processes in the room. 1. INTRODUCTION. Cleanroom design is a challenging field dominated by the need for high reliability, maintenance of strict space cleanliness requirements, life safety, and narrow temperature and humidity control bands. By necessity, efficiency is a lower priority in design.

covered are international design standards, the economics of cleanroom design, high efficiency air filtration, materials used in cleanroom construction. 6 The ISO class impacts the design, so it is important to define it at the beginning. For example, GMP compliant cleanrooms require full flush. 19 Cleanroom classifications are based on the number of particles equal to and greater than per micron (µm) in one cubic foot of air. The.